The terms that would match the blanks in the question are;
a. First messenger
b. Second messenger
c. Cyclic AMP
d. G-protein
e. Antidiuretic hormone (ADH)
What is hormone?A hormone is a chemical compound that the body's specialized cells or glands create. In order to control and coordinate many physiological processes and behaviors in organisms, hormones function as messengers. They are released into the circulation or other bodily fluids where they travel to target cells or organs where they connect to particular receptors to cause their effects.
Hormones include calcitonin, follicle-stimulating hormone, and luteinizing hormone as examples, hence the first blank's missing term is "a. First messenger."
"b. Second messengers" are signaling molecules that initiate intracellular changes within a cell.
A second messenger that is an ATP derivative is "c. Cyclic AMP."
"d. G-protein" is the enzyme complex that connects the first and second messenger.
The missing word for the fifth blank is "c. Cyclic AMP." Antidiuretic hormone (ADH) is a hormone produced by the posterior pituitary that raises cAMP levels in cells.
The missing word for the sixth blank is "e. Antidiuretic hormone (ADH)" since oxytocin, a hormone produced by the posterior pituitary, employs calcium as the second messenger.
Learn more about follicle stimulating hormone:https://brainly.com/question/28286768
#SPJ4
Here are the given terms and their corresponding definitions based on the question above:
a. First messenger - Signaling molecules outside of a cell that start extracellular changes. Examples include epinephrine, insulin, and growth hormone.
b. Second messenger - Signaling molecules inside a cell that start intracellular changes. Examples include cyclic AMP, cyclic GMP, inositol triphosphate (IP3), and diacylglycerol (DAG).
c. Cyclic AMP - A second messenger that is a derivative of ATP (adenosine triphosphate).
d. G-protein - An enzyme complex that serves as a link between the first and second messenger. It's an intracellular signaling molecule that can activate intracellular signaling pathways and cause changes in cellular behavior and gene expression
e. Antidiuretic hormone (ADH) - A hormone from the posterior pituitary that increases cAMP concentrations within a cell.
f. Oxytocin - A hormone from the posterior pituitary that uses calcium as the second messenger.
Know more about Antidiuretic hormone (ADH)
https://brainly.com/question/30762246
#SPJ11
b. Then, assuming fertilization occurs, draw and label each of the following structures in their approximate locations within the uterine tube or uterus drawn above: [18] Blastocyst, Inner cell mass of blastocyst, Morula, Ovulated secondary oocyte, Trophoblast of blastocyst, Zygote
The term fertilization is related to the process by which a sperm cell combines with an egg cell to form a zygote.
It is a biological process in which two gametes fuse, ultimately producing offspring that have combinations of genes from both parents. Fertilization occurs when a sperm penetrates an egg, causing their genetic material to merge. Following fertilization, the resulting zygote begins a series of divisions, eventually forming a blastocyst.In their approximate locations within the uterine tube or uterus drawn above, the following structures can be labeled if fertilization occurs:a) Ovulated secondary oocyteb) Zygotec) Morulad) Blastocyste) Inner cell mass of blastocystf)
Trophoblast of blastocystThe process of fertilization begins with the union of the sperm and egg cells. Once the sperm penetrates the egg's outer layer, the oocyte undergoes a series of biochemical changes to prevent the entry of additional sperm. The oocyte then divides into two haploid cells that share their genetic material to form a diploid zygote. This single cell will begin to divide quickly and eventually develop into a blastocyst, which is a hollow sphere of cells. The inner cell mass of the blastocyst is where embryonic stem cells are derived.
The trophoblast of the blastocyst gives rise to the placenta, which is necessary for the developing embryo's survival. The morula is a solid ball of cells that forms before the blastocyst, and it is where the blastocyst gets its name.
Learn more about fertilization here:https://brainly.com/question/1154065
#SPJ11
During fertilization, the sperm and egg unite to form a zygote. The zygote then undergoes several developmental stages before implanting into the uterine wall. Here are the approximate locations of the structures within the uterine tube or uterus.
Ovulated secondary oocyte: The ovulated secondary oocyte is released from the ovary during ovulation and travels to the ampulla of the uterine tube where fertilization takes place.
Zygote: After fertilization, the zygote moves through the uterine tube toward the uterus.
Morula: The zygote undergoes rapid cell division and forms a ball of cells called the morula. It takes about 3-4 days for the morula to enter the uterus.
Blastocyst: The morula continues to divide and develops into a fluid-filled structure known as the blastocyst. After approximately 5-6 days post-fertilization, the blastocyst moves toward the uterus.
Inner cell mass of blastocyst: Inside the blastocyst, the inner cell mass differentiates and forms the embryo.
Trophoblast of blastocyst: The outer layer of cells of the blastocyst, called the trophoblast, plays a crucial role in implantation.
In summary, the structures progress from the ampulla of the uterine tube for fertilization, then to the uterus for further development, with the blastocyst containing the inner cell mass and trophoblast.
Read more about fertilization
https://brainly.com/question/28585336
#SPJ11
Why is it recommended to spend more time performing the eccentric phase of contraction rather than the concentric phase of contraction?
Because muscle damage is associated with the concentric phase of contraction, time spent in the eccentric phase reduces potential muscle soreness.
The eccentric phase of a contraction focuses upon movement control and deceleration at the joint to help protect the joint from possible injury.
Because muscle is 40-to-60% stronger during eccentric contractions, increasing time during this phase elevates IGF-1 levels immediately following the training.
The muscle is 20-to-40% weaker in the eccentric phase of contraction, therefore by extending the time under tension, it increases muscle overload.
By spending more time in the eccentric phase, muscle overload is increased due to the muscle being 20-to-40% weaker during this phase, leading to greater muscle stimulation and growth. Here option D is the correct answer.
The recommended emphasis on the eccentric phase of contraction over the concentric phase is due to several reasons. One important reason is that the eccentric phase is associated with less muscle damage compared to the concentric phase.
During the concentric phase, the muscle shortens while generating force, which can lead to microtears in the muscle fibers and subsequent soreness. By spending more time in the eccentric phase, the potential for muscle soreness is reduced.
Another reason is that the eccentric phase of contraction focuses on movement control and deceleration at the joint. This helps protect the joint from possible injury by providing better stability and control during movements. The eccentric phase allows for controlled lengthening of the muscle, which can be beneficial for joint health and injury prevention.
Moreover, the eccentric phase of contraction offers additional advantages. Muscles are generally stronger during eccentric contractions, with research suggesting that they can produce 40-to-60% more force compared to concentric contractions. By increasing the time spent in the eccentric phase, the muscle can experience greater overload, leading to increased muscle growth and strength gains. Therefore option D is the correct answer.
To learn more about muscle
https://brainly.com/question/13920046
#SPJ11
Complete question:
Why is it recommended to spend more time performing the eccentric phase of contraction rather than the concentric phase of contraction?
A - Because muscle damage is associated with the concentric phase of contraction, time spent in the eccentric phase reduces potential muscle soreness.
B - The eccentric phase of a contraction focuses on movement control and deceleration at the joint to help protect the joint from possible injury.
C - Because muscle is 40-to-60% stronger during eccentric contractions, increasing time during this phase elevates IGF-1 levels immediately following the training.
D - The muscle is 20-to-40% weaker in the eccentric phase of contraction, therefore extending the time under tension, it increases muscle overload.
What prevents the female body from rejecting the
embryo/fetus, as this is a new tissue developing in her body that
is genetically different from her own tissues?
The immune system of the female body is prevented from rejecting the embryo/fetus, despite the fact that it is a new tissue growing in her body that is genetically different from her own tissues.
This is due to a number of biological mechanisms that work together to establish maternal-fetal tolerance during pregnancy. The immune tolerance mechanism is critical for the survival of the fetus in the uterus since the fetus carries a combination of maternal and paternal antigens that would usually be identified as foreign and trigger an immune response. It also prevents the mother's immune system from attacking the developing embryo by recognizing it as a threat and eliminating it.
There are several factors that contribute to maternal-fetal tolerance:
1. Trophoblast cells: These cells, which form the placenta, prevent immune cells from entering the uterus and attacking the embryo by releasing cytokines and chemokines. These factors modify the local immune response and encourage the development of a regulatory T cell phenotype.
2. HLA-G: This molecule is only expressed by the trophoblast cells of the placenta. HLA-G functions as a mediator of immune tolerance by inhibiting the proliferation of maternal T cells, NK cells, and dendritic cells.
3. Hormones: Hormones such as progesterone and estrogen aid in the establishment of immune tolerance by regulating the function of immune cells in the maternal-fetal interface. The immune cells in the uterus are affected by these hormones, which alter their expression of cytokines and chemokines.
Learn more about immune system:
https://brainly.com/question/15595309
#SPJ11
questions in a different color ink from the questions. 1.A 55 -year-old female has an arterial blood pressure reading of 155/95 mmHg. What is her pulse pressure and mean arterial pressure? Show the calculations. 2.What is the physiologic significance of capillary blood pressure? What will be a consequence if the capillary pressure is too high?
1. To calculate the pulse pressure, subtract the diastolic pressure from the systolic pressure:
Pulse Pressure = Systolic Pressure - Diastolic Pressure
Pulse Pressure = 155 mmHg - 95 mmHg
Pulse Pressure = 60 mmHg
MAP = Diastolic Pressure + 1/3 * Pulse Pressure
MAP = 95 mmHg + 1/3 * 60 mmHg
MAP = 95 mmHg + 20 mmHg
MAP = 115 mmHg
2. Capillary blood pressure plays a crucial role in facilitating the exchange of nutrients, gases, and waste products between the blood and surrounding tissues. It enables the diffusion of substances across the capillary walls and maintains an optimal environment for cellular function.
Capillary pressure is too high, it can lead to significant consequences. Firstly, increased capillary pressure can cause excessive fluid filtration from the capillaries into the interstitial spaces, leading to tissue edema. This can impair tissue function and disrupt normal cellular processes. Additionally, high capillary pressure can impair the proper flow of blood through the capillary network.
Regulation of capillary blood pressure is vital for maintaining tissue health and preventing fluid imbalance. Various mechanisms, such as vasoconstriction and dilation of arterioles, play a role in regulating capillary pressure and ensuring adequate perfusion to tissues while preventing excessive filtration or leakage.
To learn more about Blood pressure visit here:
brainly.com/question/29918978
#SPJ11
In what direction or directions does a runner move with reference to a global reference system?
A runner moves in one or more directions with reference to a global reference system.
A global reference system defines the three dimensions of space and the rotation of the earth. In general, a runner moves either north, south, east, or west, which are the cardinal directions, or in a combination of two or more directions.The direction or directions a runner moves in relation to the global reference system depends on the location of the runner and the direction in which they choose to move. For example, if a runner is moving towards the north pole, they are moving towards the northern end of the earth's axis and will be moving in a northerly direction. Similarly, if they are moving towards the equator, they will be moving in an easterly or westerly direction depending on their location.
to know more about north pole, visit:
https://brainly.com/question/536099
#SPJ11
1. The following statements relate to posture. Choose either TRUE or FALSE for statements (a)-(f) AND record the answer in your answer booklet.
a) Muscles and their tendinous attachments are the inert structures that support the body. TRUE or FALSE
b) In ideal posture the plumb line should pass through the bodies of the thoracic vertebrae. TRUE or FALSE
c) In lordotic posture the abdominal muscles are short and strong and the back
extensors are elongated and weak. TRUE or FALSE
d) Structural scoliosis involves an irreversible lateral curvature with fixed rotation of the vertebrae. TRUE or FALSE
e) In kypho-lordotic posture the cervical spine is slightly extended. TRUE or FALSE
f) In flat back posture the pelvis is in posterior pelvic tilt. TRUE or FALSE
Muscles and tendons are not inert structures, ideal posture involves the plumb line passing through the thoracic vertebrae, lordotic posture involves specific characteristics of abdominal and back extensor muscles, structural scoliosis is characterized by irreversible lateral curvature, kypho-lordotic posture involves slight cervical spine extension, and flat back posture is associated with posterior pelvic tilt.
a) FALSE
b) TRUE
c) TRUE
d) TRUE
e) TRUE
f) TRUE
a) FALSE - Muscles and their tendinous attachments are not considered inert structures. They are dynamic and actively contribute to the support and stability of the body. Muscles provide strength and control, while tendons connect muscles to bones, transmitting forces and enabling movement.
b) TRUE - In ideal posture, the plumb line, a vertical line representing gravity, should pass through the bodies of the thoracic vertebrae. This alignment helps distribute the body's weight evenly and maintains proper balance. Deviations from this ideal alignment can lead to postural imbalances and potential issues with spinal health.
c) TRUE - In lordotic posture, characterized by an exaggerated inward curvature of the lower back, the abdominal muscles tend to be short and strong. They contribute to the anterior tilt of the pelvis, which accentuates the lumbar curve. In contrast, the back extensor muscles are elongated and relatively weak, leading to an imbalance between the anterior and posterior muscle groups of the spine.
d) TRUE - Structural scoliosis refers to a permanent lateral curvature of the spine accompanied by fixed rotation of the vertebrae. It typically develops during childhood or adolescence and is not reversible through conservative measures alone. Treatment options for structural scoliosis often involve orthopedic interventions or surgery.
e) TRUE - In kypho-lordotic posture, the cervical spine maintains a slight extension, meaning it retains a gentle backward curve. This alignment helps balance the natural inward curvature of the lumbar spine, contributing to overall postural alignment.
f) TRUE - In flat back posture, the pelvis is positioned in posterior pelvic tilt. This means that the pelvis rotates backward, causing a reduction in the natural curvature of the lower back. As a result, the lumbar spine appears relatively flattened or straightened. Flat back posture can be associated with muscle imbalances and may lead to issues such as lower back pain or decreased mobility.
To know more about Muscles and inert structures here: https://brainly.com/question/25066770
#SPJ11
Kidneys are located in the following area: a. Posterior abdominal b. Inferior abdominal Inferior pelvic c. Posterior thoracic d. Anterior abdominal
Kidneys are located in the posterior abdominal area. Option A is the correct answer.
The kidneys are located in the posterior abdominal area. Specifically, they are positioned on either side of the vertebral column, behind the peritoneum, and just above the waistline. They are retroperitoneal organs, meaning they are located outside the peritoneal cavity.
The kidneys are situated on the posterior aspect of the abdomen, adjacent to the muscles of the back. They are positioned at an angle, with the left kidney slightly higher than the right kidney due to the presence of the liver on the right side. The kidneys play a vital role in filtering waste products from the blood and maintaining fluid balance in the body.
Learn more about Kidneys at
https://brainly.com/question/28021240
#SPJ4
What happened to the extracellular recording when the battery was between the voltmeter electrodes? why?
The extracellular recording decreased or became smaller when the battery was placed between the voltmeter electrodes. This is because the battery introduced a potential difference that affected the electrical activity being recorded.
1. When the battery is placed between the voltmeter electrodes, it creates a closed circuit.
2. The battery has a specific potential difference or voltage, which can interfere with the electrical signals being recorded.
3. This interference causes a change in the extracellular recording, leading to a decrease in the recorded activity.
When the battery is inserted between the voltmeter electrodes, it completes a circuit and introduces a potential difference into the system. This potential difference affects the electrical activity being recorded in the extracellular space.
Normally, the extracellular recording measures the electrical signals from cells or tissues, such as action potentials or synaptic activity. These electrical signals are typically small in magnitude and require sensitive equipment like a voltmeter to detect.
However, when a battery is placed between the voltmeter electrodes, it adds an additional voltage to the system. This added voltage interferes with the electrical signals being recorded, causing a change in the extracellular recording. Depending on the magnitude and polarity of the battery's voltage, the extracellular recording may either decrease or increase. In this case, it decreased.
This interference occurs because the battery's potential difference affects the electrical potential across the extracellular space. This alters the resting membrane potential of the cells and modifies the way electrical signals propagate through the tissue.
As a result, the extracellular recording is no longer an accurate representation of the original electrical activity. To obtain accurate recordings, it is important to remove any external sources of electrical interference, such as batteries or other devices that can introduce a potential difference into the system.
To learn more about electrodes
https://brainly.com/question/33425596
#SPJ11
Rem 200 of 200 Mark Customized subget for 200. A 24-year-old man comes to the emergency department because of a 3-day history of increasingly severe abdominal pain and vomiting. He has no history of major medical nesses hospital admissions, or operations. The patient is in obvious distress. His pulse is 110/min. On examination, his abdomen is slightly tympanitic with high-pitched bowel sounds. There is involuntary guarding on palpation. A CT scan of the abdomen shows congenital nonrotation of the bowel. Which of the following structures would have been the center visit this patient's bowel had rotated normally? A) Celiac artery B) Inferior mesenteric artery C) Median umbilical ligament D) Superior mesenteric artery E) Umbilical vein F) Urachus
d) If the patient's bowel had rotated normally, the structure at the center would have been the Superior mesenteric artery.
In normal embryological development, the bowel undergoes rotation to assume its final position in the abdomen. The Superior mesenteric artery (SMA) plays a crucial role in this rotation. It supplies blood to the midgut, which includes a significant portion of the small intestine and the proximal part of the large intestine.
In the case of congenital nonrotation of the bowel, the bowel fails to rotate properly during development. This can lead to complications such as volvulus, where the bowel twists on itself, causing obstruction and compromised blood supply. The patient's clinical presentation with severe abdominal pain and vomiting is consistent with such a complication.
Knowing the anatomy, it becomes apparent that if the bowel had rotated normally, the SMA would have been at the center. The SMA arises from the abdominal aorta and extends toward the small intestine, providing essential blood supply for proper intestinal function. In this patient, the abnormal rotation of the bowel has likely led to the development of his symptoms and the need for medical attention.
learn more about mesenteric artery here:
https://brainly.com/question/31681036
#SPJ11
Preparing a standard solution of sodium carbonate Task 1. Sodium carbonate has the formula Na.co.10H,O Calculate the relative molecular mass of Sodium carbonate. Calculation Na=23 C=12 - 16 H=1 (23x21 + (121+ (1683) + (1x2)+(10x16) 286.19 Answer glmol Calculate the amount of Sodium carbonate required to make 100cm' of a 0.25M solution Calculation: 100ml=0.12 10.1 x 0.25 0.025 mol mass Na2CO3.10 H2O=0.025 x 286.19 Answer 7.15489 Accurately weigh the appropriate amount on an electronic balance in a weighing boat. Transfer into a conical flask and add 100cm of deionised water using a 100cm measuring cylinder. Gently swirl the mixture until the sodium carbonate dissolves. Calculate the moles of Sodium carbonate you would have in 10cm of a 0.25M solution Calculation: 10ml= 0.01 Na2CO3 = n Na 2 CO3.10 20 = 0.01L x 0.25 mol Answer 0.0025 mol Task 2 Using a standard solution of sodium carbonate to find the concentration of hydrochloric acid. Using a measuring cylinder add 10cmn of sodium carbonate into a conical flask. Add 4 drops of indicator solution. Add hydrochloric acid of unknown concentration to the burette a few drops at a time with swirling until the end-point is reached. expt initial/cm final / cm titre / cm 1 N o 5.2 mbia Man 9 5.2 5.2 9. olanos 13.5 multe 4.5 3.8 man 3 العيا average of concordant results 4.5 Find the concentration of hydrochloric acid in the burette. Calculation: Sodium carbonate moles = 0.0025 Average = 4.5 : 1000 0.0025 = 0.0045
The concentration of HCl in the burette is 0.0125 M.
Relative molecular mass of Na2CO3.10H2O = (2 x 23) + 12 + (3 x 16) + (10 x (2 + 16))
= 286.19 g/mol
Amount of Na2CO3.10H2O required to make 100 mL of a 0.25 M solution = 100 mL x 0.25 mol/L = 0.025 moles
Mass of Na2CO3.10H2O required = 0.025 moles x 286.19 g/mol = 7.15489 g
When 7.15489 g of Na2CO3.10H2O is dissolved in 100 mL, the molar concentration of Na2CO3.10H2O = 0.25 M.
The moles of Na2CO3.10H2O present in 10 mL of 0.25 M solution is = 0.25 x 10⁻³ L x 0.25 moles/L = 0.000625 moles
Initial burette reading = 5.2 mL
Final burette reading = 9.0 mL
Volume of HCl delivered = 9.0 - 5.2 = 3.8 mL
From the balanced equation, it is known that 1 mole of Na2CO3 reacts with 2 moles of HCl.
The moles of HCl that reacted with Na2CO3 = (0.000625 moles/2) = 0.0003125 moles
Volume of HCl that would have reacted with 1 mole of Na2CO3 = 25 mL
Therefore, concentration of HCl = (0.0003125 moles/25 mL) x 1000 mL/L = 0.0125 M
The concentration of HCl in the burette is 0.0125 M.
Learn more about Titration:
https://brainly.com/question/11819143
#SPJ11
Arrange the sequence of events that occurs during the excitation stage of muscle contraction in the correct order. Start with "An action potential arrives at the terminal end of a motor neuron axon."
#1The spread of depolarization along the transverse tubules promotes the opening of voltage-gated Ca2+ channels located along the T tubules and the terminal cisternae of the sarcoplasmic reticulum.
#2 Synaptic vesicles containing acetylcholine (ACh) release neurotransmitters into the synaptic cleft.
#3Ligand-gated Na+ channels open which allows for an influx of Na+ into skeletal muscle fiber.
#4ACh binds to ACh receptors on the sarcolemma of skeletal muscle fiber. The receptors are coupled to ligand-gated channels. #5Membrane potential of the sarcolemma of skeletal muscle fiber reaches threshold.
#6 Voltage-gated Na+ channels along the sarcolemma open leading to further influx of Na+. This influx of Na+ triggers the firing of an action potential that spreads along the sarcolemma of the muscle fiber and down the transverse (T) tubules into the sarcoplasm of the muscle fiber.
#7 An action potential arrives at the terminal end of a motor neuron axon.
#8 Influx of Ca2+ ions into the synaptic knobs of the motor axon.
#9 Depolarization sweeps into the synaptic knobs of a motor axon and triggers the opening of the voltage gated Ca2+ channels. #10 Influx of Ca2+ from the sarcoplasmic reticulum increases the intracellular concentration of Ca2+ in the sarcoplasm.
#11 The sarcolemma of skeletal muscle fiber depolarizes, leading to the generation of an end plate potential.
During the excitation stage of muscle contraction, an action potential arrives at the motor neuron, leading to the release of acetylcholine (ACh). ACh binds to receptors on the muscle fiber, causing ligand-gated Na+ channels to open, resulting in depolarization of the sarcolemma.
The correct sequence of events during the excitation stage of muscle contraction is as follows:
1. An action potential arrives at the terminal end of a motor neuron axon.
2. Synaptic vesicles containing acetylcholine (ACh) release neurotransmitters into the synaptic cleft.
3. ACh binds to ACh receptors on the sarcolemma of skeletal muscle fiber. The receptors are coupled to ligand-gated channels.
4. Ligand-gated Na+ channels open, allowing an influx of Na+ into the skeletal muscle fiber. This depolarizes the sarcolemma.
5. The depolarization spreads along the sarcolemma and down the transverse (T) tubules.
6. The spread of depolarization along the transverse tubules promotes the opening of voltage-gated Ca2+ channels located along the T tubules and the terminal cisternae of the sarcoplasmic reticulum.
7. Influx of Ca2+ from the sarcoplasmic reticulum increases the intracellular concentration of Ca2+ in the sarcoplasm.
8. The increased intracellular Ca2+ concentration triggers the subsequent events of muscle contraction.
Note: The given sequence of events is rearranged to reflect the correct order.
learn more about "contraction":- https://brainly.com/question/25778330
#SPJ11
Which of the following is an INCORRECT statement? (Check all that apply) (A) Ventricles receive blood coming to the heart while atria pump it out of the heart. (B) The fibrous skeleton separates the heart muscle into two functional units: the atrial myocardium and the ventricular myocardium. (C) In both puimonary and systemic circulations, oxygen-rich blood is carried by aneries and oxygen-poor blood is carried by veins. (D) The venae cavae take blood away from the heart and the aorta returns it to the heart. (E) Papillary muscles and chordae tendineae prevent semilunar valves from everting. (F) The stroke volume is the difference between the end-diastolic volume and the end-systolic volume. (G) The Dicrotic notch is a slight inflection in the arterial pressure during isovolumetric contraction. (H) During isovolumetric contraction, the ventricular pressure is rising, but the semilunar valves are still close. (I) During isovolumetric relaxation, the ventricular pressure is dropping, but the atrioventricular valves are still close. (J) Atrial systole occurs at the beginning of the ventricular diastole.
The incorrect statements are:
(A) Ventricles receive blood coming to the heart while atria pump it out of the heart.
(D) The venae cavae take blood away from the heart and the aorta returns it to the heart.
(J) Atrial systole occurs at the beginning of the ventricular diastole.
Option A: This statement is incorrect. The ventricles of the heart do not receive blood coming to the heart; rather, they pump blood out of the heart. The atria, on the other hand, receive blood returning to the heart.
Option D: This statement is incorrect. The venae cavae are large veins that bring blood back to the heart from the body, while the aorta is the main artery that carries oxygenated blood away from the heart to supply the rest of the body.
Option J: This statement is incorrect. Atrial systole refers to the contraction of the atria, which occurs during ventricular diastole or relaxation when the ventricles are filling with blood. It does not occur at the beginning of ventricular diastole.
Option A, D, and J are incorrect.
You can learn more about heart at
https://brainly.com/question/26387166
#SPJ11
plate , lars , et al . , " small molecule proteostasis regulators that reprogram the er to reduce extracellular protein aggregation " , elife , vol . 5 , ( jul . 20 , 2016 ) , 49 pgs
Proteostasis refers to the cell's ability to maintain the appropriate balance of correctly folded and functional proteins with misfolded and/or damaged proteins. As a result, protein aggregates and misfolded proteins can result in various diseases, including Alzheimer's and cystic fibrosis.
A recent study by Plate, Lars, et al. provides insight into a new class of small molecules that can serve as "proteostasis regulators" that can reprogram the endoplasmic reticulum (ER) to lessen extracellular protein aggregation. The research examined two small molecules, N-(1,3-dimethylbutyl)-N'-(3-phenylpropyl)-thiourea (TRIB3) and pyrvinium pamoate, both of which are capable of reducing protein aggregation. They do this by modifying protein synthesis and reducing protein loading in the ER by inhibiting the protein translation and ribosome biogenesis. Both compounds have shown promising results in mice, with evidence of decreased protein aggregation and improved proteostasis in their organs. More research is needed to determine if these small molecules can help to develop drugs for treating diseases associated with protein aggregation, and this could serve as a starting point. This approach to regulating protein folding and aggregation may be significant in the development of novel treatments for neurodegenerative, metabolic, and other diseases in which protein aggregation is a significant factor.
To know more about Proteostasis visit:
https://brainly.com/question/33815758
#SPJ11
Describe the mitotic clock theory of cellular aging and how it supports the evolutionary theory of aging. What is the major argument against the mitotic clock theory of cellular aging as a model for whole-organism aging?
The mitotic clock theory of cellular aging suggests that aging results from a reduction in the number of times a cell can undergo mitosis. When a cell divides, the telomeres, which are protective caps on the end of the chromosomes, shorten.
In this way, the number of times a cell can divide is limited, and this is thought to be a major factor in the aging process. The mitotic clock theory supports the evolutionary theory of aging, which suggests that aging is a result of natural selection favoring genes that are beneficial for reproduction and survival early in life but have negative effects later in life.
The mitotic clock theory suggests that the limited number of cell divisions is an adaptation that evolved to prevent the development of cancer, which is caused by uncontrolled cell growth and division. The major argument against the mitotic clock theory of cellular aging as a model for whole-organism aging is that not all cells have a limited number of divisions.
Additionally, some organisms, such as certain species of turtles and whales, have been found to have telomeres that do not shorten with age. Therefore, while the mitotic clock theory may be a factor in cellular aging, it may not fully explain the aging process at the whole-organism level.
Learn more about clock theory
https://brainly.com/question/31118893
#SPJ11
Which of the following statements are true of chemical blood clotting? (Read carefully and select all the correct statements.) a) Many of the clotting factors are produced by the liver, but some are produced by the spleen.
b) Fibrinogen is changed to fibrin in stage 1 of clotting.
c) Calcium ions are needed for all three stages of clotting.
d) Prothrombin activator changes thrombin to prothrombin.
e) The actual clot is made of fibrin.
f) The purpose of clot retraction is to create a smaller area to be repaired.
g) The purpose of fibrinolysis is to strengthen a newly formed clot.
h) The endothelium of blood vessels is smooth and helps prevent abnormal clotting.
The following statements are true of chemical blood clotting: Many of the clotting factors are produced by the liver, but some are produced by the spleen.
Fibrinogen is changed to fibrin in of clotting. Calcium ions are needed for all three stages of clotting .The actual clot is made of fibrin.The purpose of clot retraction is to create a smaller area to be repaired. The endothelium of blood vessels is smooth and helps prevent abnormal clotting. Chemical blood clotting is the method that involves many chemical reactions to prevent blood loss.
Platelets, which are cell fragments from the bone marrow, are mainly responsible for the primary response of clotting after an injury. In this process, the platelets in blood become "sticky" and form a temporary patch that seals the break in the vessel wall. Chemical clotting occurs in three stages Fibrinogen changes to fibrin. - Prothrombin activator changes prothrombin to thrombin. Fibrin is converted into a clot. Calcium ions are essential for all three of these processes.Many of the clotting factors are produced by the liver, but some are produced by the spleen.
To learn more about Fibrinogen visit here:
brainly.com/question/1882546
#SPJ11
17. Which of the following joints is a symphysis joint? A) Intervertebral joint B) Costovertebral joint C) Shoulder joint D) Knee joint E) Ankle joint 18. Which of the followings is not a typical feature of synovial joints? A) Articular capsule B) Fibrous cartilage C) Synovial fluid D) Synovial membrane E) Bursae
The following joint is a symphysis joint: Intervertebral joint Symphysis joint is a cartilaginous joint in which bones are connected by a disc of fibrocartilage. The answer is (A).
These joints are immovable or limited in movement. Fibrocartilage is present in symphysis joints where strength and stability are necessary, such as the joint between the pubic bones. The intervertebral joint is an example of a symphysis joint. Answer: A) Intervertebral jointThe option B) Costovertebral joint is incorrect. The costovertebral joint is a synovial joint and is a joint between the thoracic vertebrae and the rib. They are also known as gliding joints. Answer to the second question: B) Fibrous cartilage is not a typical feature of synovial joints. Synovial joints are joints in which two bones are separated by a space filled with synovial fluid. Synovial fluid is present in synovial joints and it is the fluid secreted by the synovial membrane which is responsible for lubrication. The articular capsule, synovial fluid, synovial membrane, and bursae are typical features of synovial joints. Option B) Fibrous cartilage is not a typical feature of synovial joints.
To learn more about Symphysis joints here
https://brainly.com/question/30895114
#SPJ11
Mrs Angèle consults you about nausea; during the visit, you take note of the following signs: -occasional vomiting – impossibility to relax – heart palpitations (fright) - insomnia - dizziness -oppression of the thorax
Choose the right energetic diagnosis
A Humidity-heat of the gall bladder
B Empty gall bladder
C Empty lungs
D Yang heat of the heart
Yang heat of the heart is the right energetic diagnosis for the given symptoms. An energetic diagnosis is a method of assessing a person's health and well-being in terms of energy imbalances.
Traditional Chinese Medicine (TCM) believes that energy, or Qi, circulates through the body and is responsible for a person's physical, mental, and emotional well-being. When this energy is disrupted or imbalanced, symptoms such as nausea and insomnia may occur.Signs of yang heat of the heart: According to TCM, the heart is responsible for circulating Qi and blood throughout the body. When there is an imbalance of heat in the heart, it can lead to symptoms such as palpitations, insomnia, dizziness, and oppression of the thorax.
Occasional vomiting may also occur due to the heat rising up to the throat. The symptoms mentioned in the question all point to an imbalance of yang heat in the heart, making it the right energetic diagnosis.Other options are incorrect because:Humidity-heat of the gallbladder can lead to symptoms such as a bitter taste in the mouth and a sensation of heat in the body.Empty gallbladder can lead to symptoms such as anxiety and irritability.Empty lungs can lead to symptoms such as shortness of breath and a weak voice.
Learn more about heat:
https://brainly.com/question/30647838
#SPJ11
62 minutes rema 10 4 Points Question 23 The enhanced ability of the sperm to fertilize the ovum is due to the process of capacitation. In vitro studies indicate that the sperm can fertilize the ovum it sperm are first washed before being introduced to the ovum. Based on this observation, it suggest that A. the process of capacitation is temperature dependent B. the process involves the removal of some inhibiting substances from the sperm C. in capacitation, secretions of the female reproductive tract are taken up by the sperm D. pH is an important factor in the process of capacitation E. only sperm that come into contact with vaginal secretions are capable of fertilizing an ovum
The statement that in vitro studies indicate that the sperm can fertilize the ovum if sperm are first washed before being introduced to the ovum suggests that the process involves the removal of some inhibiting substances from the sperm. Hence, option B is the correct answer.
The process of capacitation refers to a complex process of biochemical and physiological changes that occur in the sperm when they are in the female reproductive tract (FRT) for a specific time period. The main goal of this process is to make the sperm gain the ability to fertilize the oocyte.
A few factors that are involved in capacitation are as follows: The removal of glycoprotein coat from the sperm membraneIncrease in the motility of sperm, Removal of inhibiting substances from the sperm membrane, and An influx of calcium ions from the extracellular fluid.
In vitro fertilization studies indicate that capacitation can be simulated by washing the sperm with a special medium that contains various biochemical agents to mimic the female reproductive tract's environment. Therefore option B is the correct answer.
To learn more about sperm
https://brainly.com/question/25282799
#SPJ11
11. The cornea is a continuation of the A. Retina B. Choroid C. Iris 7 D. Sclera E. Optic (II) nerve 12. Which one of the following listed is NOT part of the vascular tunic of the eye? A. Choroid B. Ciliary body C. Ora serrata 2 D. Iris 14. The optic disc marks the A. Attachment of the extrinsic eye muscles B. Attachment of the lens to the ciliary body Exit of the optic (II) nerve C. D. Boundary between retina and iris 15. The visual receptors known as cones are A. Most concentrated in the optic disc B. Absent from the fovea centralis. C. Stimulated by high-intensity illumination D. Found in the choroid 16. When swimming underwater, if you open your eyes, it is impossible to focus clearly on any object. The reason for this is A. The cornea can no longer function as a refractive interface because the density of water and that of tissue is too close. B. The pressure of water tends to distort the cornea inward C. The degree of refraction produced by the cornea becomes too large to effectively bend light rays D. The lens cannot change in shape when placed in water E. Both A and C 17. The four refracting media of the eye, listed in the sequence in which they retract light, are art to notcunos ei samo bit 1. Vitreous body 2. Lens 3. Aqueous humor 4. Cornea A 1, 2, 3, and 4 B. 4, 1, 2, and 3 C. 4, 3, 2, and 1 D. 2, 3, 4, and 1 E. 3, 2, 1, and 4 18. Binocular vision permits A. Convergence B. Accommodation C. Depth perception D. Refraction 19. Which one of the following is NOT correct of the image that falls on the light-sensitive part of the eye? A. Inverted B. Reversed C. Smaller the farther away the object is from the eye D. Reduced in size E. All of the above are correct. 20. In the accommodation reflex for close-up vision, what adjustments are made? A. The ciliary muscles contract, the lens becomes move convex, and the pupil constricts B. The muscles of the ciliary body reflex, the lens becomes less convex and the sphincter of the pupil relaxes. C. The ciliary muscles contract, tightening the suspensory ligaments, the lens flattens, and the pupil becomes dark adapted. D. The ciliary muscles contract. E. The extrinsic muscles contract, the lens does not change, but the radial muscle relax. 21. At what point in the visual system does the greatest bending of the light rays occur? A. As light enters the cornea B. As light leaves the cornea to enter the aqueous humor C. As light enters the lens D. As light leaves the lens E. The amount of bending is identical in each of the above.
The cornea is a continuation of the Sclera.
The cornea, the transparent outermost layer of the eye, is a continuation of the sclera. The sclera is the tough, fibrous, white outer layer of the eye that provides structural support and protection. The cornea is located at the front of the eye and covers the iris, pupil, and anterior chamber. It is responsible for refracting light and plays a crucial role in focusing incoming light onto the retina for vision.
The cornea and sclera are made up of similar connective tissues, but the cornea is thinner and more transparent. It allows light to enter the eye and undergoes the initial bending (refraction) of light rays.
The cornea's curvature helps to focus light onto the lens, which further refracts the light onto the retina, where the image is formed.
Learn more about cornea
brainly.com/question/29366850
#SPJ11
This is a multiple-multiple. SELECT ALL CORRECT ANSWERS
based on what you learned from the text, which of the following drugs will DECREASE the input that the small intestine receives from the parasympathetic pathway
a) nicotinic acetylcholine receptor antagonist
b) muscarinic acetylcholine receptor antagonist
c) nicotinic acetylcholine receptor agonist
d) muscarinic acetylcholine receptor agonist
Muscarinic acetylcholine receptor antagonist will decrease the input that the small intestine receives from the parasympathetic pathway.
Muscarinic acetylcholine receptor antagonists, also known as anticholinergic drugs, are substances that block the action of acetylcholine on muscarinic receptors. Acetylcholine is a neurotransmitter that plays a role in stimulating the parasympathetic nervous system, which is responsible for promoting the activity of the small intestine.
By blocking the muscarinic acetylcholine receptors, these drugs decrease the input that the small intestine receives from the parasympathetic pathway. This leads to a reduction in the activity of the small intestine, including a decrease in its contractility and secretion.
Learn more about acetylcholine receptor
brainly.com/question/12496352
#SPJ11
If you gram stained human cells, what do you think the results would look like? think about the different steps in the staining procedure and how thry are working
Gram staining human cells would not produce meaningful results because human cells do not have cell walls, which is the target of Gram staining.
Gram staining is a widely used differential staining technique that allows the identification of bacterial cells based on the structural characteristics of their cell wall. The staining procedure involves several steps, including crystal violet staining, iodine fixation, alcohol decolorization, and counterstaining with safranin. When it comes to human cells, however, Gram staining would not produce meaningful results because human cells do not have cell walls.
Instead, they have a plasma membrane that separates the inside of the cell from its surroundings and a cytoskeleton that provides structural support and helps in cell division, among other functions. Therefore, in the absence of cell walls, the crystal violet-iodine complex would not form and the cells would not retain the stain, rendering the staining procedure ineffective for human cells.
Learn more about Gram staining here:
https://brainly.com/question/14969595
#SPJ11
Explain the stress response in the body. How does it begin, what
part of the body initiates the stress response, what
chemicals/hormones are released, and what happens during the
response to our body?
The stress response is an automatic reaction of the body to an actual or perceived threat that causes physical, emotional, and psychological changes. This response is known as the “fight or flight” response, and it is activated when the hypothalamus in the brain detects a stressor.
The hypothalamus then activates the sympathetic nervous system (SNS), which initiates the stress response. The SNS signals the adrenal medulla to release epinephrine (adrenaline) and norepinephrine into the bloodstream. These hormones prepare the body to fight or flee by increasing heart rate, breathing rate, and blood pressure. They also divert blood flow away from the digestive and reproductive systems and towards the muscles and limbs, providing energy for action. During the stress response, the body also releases cortisol, which is a stress hormone produced by the adrenal cortex. Cortisol increases blood sugar levels, suppresses the immune system, and helps the body to use fat and protein for energy. It also helps to maintain blood pressure and cardiovascular function in response to stressors. The stress response can be helpful in dangerous situations, allowing the body to respond quickly and effectively to potential threats. However, chronic stress can be harmful to health, leading to a range of physical and psychological problems, including anxiety, depression, high blood pressure, heart disease, and diabetes.
To learn more about the hypothalamus here
https://brainly.com/question/32900534
#SPJ11
Thomas rides in an elevator with a young child suffering from the common cold. Like most young children, the sick girl fails to cover her mouth when she sneezes thus releasing cold viruses (Rhinoviruses) into the air of the elevator. Thomas has the misfortune of inhaling one of those viruses. These questions follow step-wise as Thomas' immune system attempts to prevent the infection 1)Identify three physical barriers in Thomas' nasal cavity that attempt to prevent infection by the virus.
The physical barriers in Thomas' nasal cavity that attempt to prevent infection by the virus are: Nasal hair, mucous membranes, and cilia.
The human respiratory system is a complex network of organs that are responsible for breathing and the exchange of oxygen and carbon dioxide between the body and the environment. It's a protective system that has several physical and chemical barriers that protect against various airborne infections. One of the most significant physical barriers of the respiratory system is the nasal cavity. Here are the three physical barriers in Thomas' nasal cavity that attempt to prevent infection by the virus:Nasal hair Mucous membranes Cilia.
These structures act as physical barriers that help in the process of filtering, trapping, and expelling the harmful particles and pathogens from the respiratory tract. The nasal hair filters the air by trapping larger particles like pollen and dust. The mucous membranes produce mucus, which traps the airborne pathogens, viruses, and bacteria, and prevents them from entering into the lungs. Lastly, the cilia are tiny hair-like structures that move back and forth, sweeping the trapped mucus and pathogens out of the respiratory system.
Learn more about physical barriers:
https://brainly.com/question/32221787
#SPJ11
1. Describe the respiratory pattern for normal breathing. Include in your description the characteristics of thel 4 pts trace such as the rate (Table 1), and the relative duration of inspiration (breathing in) and expiration (breathing out) (Table 2). How do the inspiration and expiration times compare to to what is expected for normal breathing based on the rhythm set by our medullary respiratory centre and attempt to explain any differences. Enter your answer here r B i x₂x²
The respiratory pattern for normal breathing: Breathing, or ventilation, is a physiological process of exchanging gases between an organism and its environment.
In humans, normal breathing involves the following characteristics:The average respiratory rate is about 12-16 breaths per minute, with a standard deviation of about 2-3 breaths per minute.The relative duration of inspiration and expiration is roughly equal, with inspiration being slightly longer than expiration.Inspiration is active, and expiration is passive (i.e., no muscular effort is required).The rhythm of normal breathing is generated and controlled by the medullary respiratory centre in the brainstem.
This increase results in shorter expiration times to allow for the rapid elimination of carbon dioxide. Conversely, when there is a decrease in carbon dioxide levels, the respiratory rate decreases, and the tidal volume increases, resulting in longer expiration times.
Learn more about respiratory pattern here: respiratory pattern
#SPJ11
2. Present an essay in 200 words, Arial Narrow 14 and margins of 1" with your explanation to: O Cocaine use causes vasoconstriction. Is this likely to increase or decrease blood pressure, and why?
Consuming cocaine can lead to the narrowing of blood vessels, causing vasoconstriction and subsequently increasing blood pressure.
The constriction of blood vessels reduces the space available for blood to flow, resulting in greater resistance to blood flow and a subsequent rise in blood pressure.
Sustained elevation of blood pressure can have detrimental effects on the body's organs and systems.
Therefore, it is important to avoid using cocaine in order to prevent the negative consequences it has on the body.
To summarize, cocaine use induces vasoconstriction, elevates blood pressure, and can pose significant risks to overall health if continued.
Hence, it is crucial to abstain from cocaine use.
Read more about vasoconstriction
https://brainly.com/question/13258282
#SPJ11
Select all statements that are true about allosteric agonists
O nicotine is an example of one
O bind to a different site than the endogenous (natural) neurotransmitter
O directly activate receptors
O require orthosteric to function
Allosteric agonists are true for the following statements:
1. Nicotine is an example of one
2. Bind to a different site than the endogenous (natural) neurotransmitter
Allosteric agonists are a type of ligand that bind to a specific site on a receptor different from the site where the endogenous neurotransmitter binds. This unique binding site is called the allosteric site. Unlike orthosteric agonists, which directly activate the receptor by binding to its orthosteric site, allosteric agonists modulate the activity of the receptor by inducing conformational changes in the receptor structure.
One important characteristic of allosteric agonists is that they require the presence of the endogenous neurotransmitter to be effective. This means that they enhance or potentiate the effect of the natural neurotransmitter when it binds to the orthosteric site. Without the orthosteric site activation, allosteric agonists alone cannot directly activate the receptor.
Nicotine serves as an example of an allosteric agonist. It binds to the nicotinic acetylcholine receptor and potentiates the effect of acetylcholine, the natural neurotransmitter. By binding to the allosteric site, nicotine increases the receptor's sensitivity to acetylcholine, resulting in enhanced neurotransmission.
In summary, allosteric agonists bind to a distinct site on the receptor, require the presence of the endogenous neurotransmitter for their effect, and modulate receptor activity by inducing conformational changes. Their role is to enhance the response to the natural neurotransmitter rather than directly activating the receptor on their own.
To know more about Allosteric agonists here: https://brainly.com/question/13708316
#SPJ11
4. Exercise 3.4. Genetic Testing and Insurance Prices. Suppose the likelihood that a person will get disease X is determined in large part (but not exclusively) by his or her genes. Initially, it Is impossible to determine who carries the gene for the disease, and many people spend $500 on special health insurance to cover the costs of treatment for the disease. Suppose scientists uncover the gene responsible for the disease and develop a simple test for the gene. (Related to Application 3.) a. Suppose the government passes a law that prevents insurance companies from getting the results of a customer's genetic test for X. Will the new price of X insurance be greater that or less than $500 ? b. Suppose insurance companies have access to the results of genetic tests and they require all customers to get the test. How will the insurance company change its price of X insurance?
The first scenario's price of X insurance will be greater than $500, while the second scenario's price of X insurance depends on the results of the genetic test.
a) If the government passes a law that prevents insurance companies from getting the results of a customer's genetic test for X, the new price of X insurance will be greater than $500.
b) If insurance companies have access to the results of genetic tests and they require all customers to get the test, the insurance company will change its price of X insurance as follows: if the test shows that a customer has the gene, the insurance company will raise the price of insurance to $800 to cover the expected treatment cost of $10,000 (with probability 1). In contrast, if the test shows that a customer does not have the gene, then the insurance company will lower the price of insurance to $100 to cover only administrative costs, assuming there is no risk of developing the disease.
According to these two scenarios, the first scenario's price of X insurance will be greater than $500, while the second scenario's price of X insurance depends on the results of the genetic test.
Know more about Genetic Testing
https://brainly.com/question/30336854
#SPJ11
The phenomenon in which a gene's expression is determined by its parental origin is called:_____.
The phenomenon in which a gene's expression is determined by its parental origin is called genomic imprinting.
Genomic imprinting is a phenomenon in which the expression of a gene is dependent on the sex of the parent from which it is inherited. That is, the gene's expression is influenced by the parent from which it was inherited. This condition is frequently observed in mammals and flowering plants, but not in invertebrates.
The genomic imprinting phenomenon is believed to have evolved as a mechanism for resolving parent-offspring disputes over nutrient distribution during development.
Maternal and paternal genes will often have different interests in this battle, and the resulting imprinting phenomenon is believed to be a way for these different interests to be reconciled and for the developing offspring to be kept in check.
To know more about genomic imprinting visit:
https://brainly.com/question/31847913
#SPJ11
Why did systolic pressure increase due to exercise? (Select all that apply) PLEASE MAKE SURE ITS CORRECT
Check All That Apply
a. Exercise utilizes the skeletal muscle pump to increase in venous return to the heart.
b. Exercise causes the release of positive inotropic agents.
c. Exercise stimulated the sympathetic division which causes constriction of the veins.
d. Exercise causes an increase in heart rate.Exercise causes an increase in heart rate.
e. Exercise causes an increase in systemic peripheral resistance.
The correct options are:
a. Exercise utilizes the skeletal muscle pump to increase venous return to the heart.
b. Exercise causes the release of positive inotropic agents.
d. Exercise causes an increase in heart rate.
e. Exercise causes an increase isystemic n peripheral resistance.
Skeletal muscle is a type of muscle tissue that is attached to bones and plays a crucial role in body movement and posture. It is also known as voluntary muscle because it is under conscious control. Skeletal muscles are composed of long, cylindrical fibers that are multinucleated. These muscle fibers are organized into bundles called fascicles, which are surrounded by connective tissue layers.
Skeletal muscle is characterized by its striated appearance, which is due to the alternating pattern of light and dark bands called sarcomeres. Sarcomeres are the functional units of muscle contraction and are made up of thick myosin filaments and thin actin filaments. Skeletal muscles work in pairs or groups to produce coordinated movements and are attached to bones via tendons.
To learn more about Skeletal muscle visit here:
brainly.com/question/31182318
#SPJ11
When choosing an isotype control antibody for a flow cytometry experiment, which of the following does NOT need to match your antibody in your specific antibody stain? a. the host species of the antibody b. the isotype class c. the conjugated fluorochrome d. the epitope bound by the Fab region e. the dilution used in the staining cocktail
When choosing an isotype control antibody for a flow cytometry experiment, the epitope bound by the Fab region does NOT need to match your antibody in your specific antibody stain. The correct option is d.
Isotype controls are antibodies that bind to an irrelevant antigen or to a surface that is not expressed in the tested cells. In a flow cytometry experiment, isotype controls are utilized to help researchers differentiate between true and false positive staining. They also assist in determining the background level of the sample being analyzed.
The isotype control antibody should have all the properties of the primary antibody except for the specific binding to the target of interest. The host species, isotype class, conjugated fluorochrome, and dilution used in the staining cocktail must be matched with the primary antibody for effective results. The epitope bound by the Fab region, on the other hand, does not need to be matched. Hence, d is the correct option.
You can learn more about epitope at: brainly.com/question/32216146
#SPJ11